← Projects
Ex Vivo Peripheral Simulating Bioreactor
CompletedBiomedical EngineeringFluid DynamicsControl Systems
A bioreactor system that simulates cardiovascular and biomechanical conditions of peripheral arteries for testing endovascular devices without animal models.
- Alternative to in-vivo animal testing for endovascular devices
- Replicates physiological flow conditions
- Validated through pharmacokinetic studies of drug-eluting stents
- Published in Bioengineering & Translational Medicine
- System adopted for ongoing research applications
Related Publication
Chen, D., et al. "Design and use of an ex vivo peripheral simulating bioreactor system for pharmacokinetic analysis of a drug coated stent." Bioengineering & Translational Medicine, 2024.